- 1). Place your palm flat on the top of the Drano cap and press down while turning the cap counterclockwise. Do not squeeze the bottle.
- 2). Pour approximately 16 ounces -- one-half of a 32-ounce bottle -- of Drano directly into a drain that is moderately clogged or slow-running. Pour approximately 32 ounces -- a full bottle -- directly into a severely clogged drain.
- 3). Let the Drano work 15 minutes for moderate clogs or 30 minutes for severe clogs.
- 4). Turn on the hot water tap and flush the affected drain with hot water.
- 5). Pour an additional 16 to 32 ounces of Drano in the drain, wait 15 to 30 minutes and flush again with hot water if the drain fails to clear. Repeat this procedure until the drain clears.
- 6). Replace the lid on your bottle of Drano by turning the lid clockwise until it snaps.