- 1). Identify the weed that you are trying to get rid of, as this will assist you in finding the most effective weed killer for the plant. You can find pictures and descriptions of various weeds at websites such as Weed Science, from the University of Illinois Extension.
- 2). Water your garden 24 hours before spraying any weed killer, and be sure it's not going to rain for at least a day, so that your solution will have time to work.
- 3). Choose your method of spreading the weed killer. At this point, there is not a way to broadly spread a homemade product that will only kill weeds and not grass. Therefore, you must have a way of spraying a small area at a time.
- 4). Fill a spray bottle with one part vinegar three parts water, with a few drops of liquid dish detergent to allow to fuse to the leaves. According to Don Comis, from the USDA Agricultural Research Service, vinegar was proven to be an affective weed killer. For tougher weeds, use a stronger vinegar concentrate. Spray vinegar directly on the leaves and roots of the weeds, being careful not to spray the other plants. You can also use a sponge brush to apply the vinegar directly on the weeds.
- 5). Pour boiling water over any large area where you wish to destroy all vegetation. This is a safe way to remove weeds from their roots but leave the area safe to replant.
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