- In healthy people, the pancreas produces insulin in the amount necessary to allow the body to remove glucose from the blood stream. People with type 1 diabetes need injectable insulin; people with type 2 diabetes may need insulin when the disease progresses.
- Losing weight, exercising and following a diet such as DASH (Dietary Approaches to Stop Hypertension) that provides plenty of fruits, vegetables and fewer fats and refined sugars can help people maintain and regain their metabolic health.
- Chlorpropamide, glipizide (Glucotrol from Pfizer), glimepiride (Amaryl from sanofi aventis), repaglinide (Prandin from Novo Nordisk), and nateglinide (Starlix from Novartis) induce the pancreas to produce more insulin.
- Metformin, pioglitazone (Actos from Takeda), and rosiglitazone (Avandia from GlaxoSmithKline) make muscle tissue more sensitive to insulin, meaning the muscles can remove more glucose from the blood stream.
- Exanatide (Byetta from Lilly) and sitagliptin (Januvia from Merck) keep an essential hormone known as glucagon-like peptide 1(GLP-1) circulating in the blood.
- Acarbose (Precose from Bayer) and meglitol (Glyset from Pfizer) prevent the digestion of many forms of carbohydrates (i.e., starches), including table sugar.
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