- The ASPCA states that even in small doses ibuprofen can result in gastrointestinal bleeding, stomach ulcers and potentially kidney failure depending on the amount of medication ingested. At 50mg per pound gastric symptoms occur, and at 150 mg per pound kidney failure can result. Repetitive smaller doses can have a cumulative effect and result in toxicity.
- Signs that your dog might be suffering from ibuprofen toxicity include vomiting, diarrhea, lethargy or depression, stumbling and not eating. A dog exhibiting these symptoms needs veterinary attention to provide supportive care.
- Dogs are particularly susceptible to ibuprofen toxicity--especially the stomach ulcers. These can occur as soon as 12 hours after ingestion, or can take as long as five days to become apparent.
- Supportive care for ibuprofen ingestion in dogs includes administration of IV fluids and medication that will protect the stomach lining and decrease vomiting. If the bleeding ulcer is severe, a blood transfusion might be needed. If the kidneys have been affected, IV fluids are necessary for recovery.
- To prevent ibuprofen toxicity in dogs, never administer it to your dog. Keep the medication in a safe place where the dog cannot get to it.